Polypill, bloodstream infections, Paxlovid, and treating acute sinusitis

This week's topics include a polypill for HTN following stroke, clinical impact of rapid tests for gram negative bloodstream infections, is there any remaining role for Paxlovid, and treating acute sinusitis.

Program notes:

0:30 Controlling HTN after intracerebral hemorrhage

1:30 Triple pill or placebo

2:30 Only effective treatment is lowering blood pressure

3:32 Serum creatinine levels

4:15 Is there a role for Paxlovid?

5:15 Did not reduce hospitalization or death

6:10 Fast antimicrobial susceptibility test for gram negative

7:10 Desirability of outcome ranking or DOOR

8:10 Median time to effective therapy reduced

9:10 Was not superior

10:07 Acute sinusitis treatment

11:15 Secondary effects higher with augmentin

12:21 End

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PPIs, kidney function equations, DVT, and timing of exercise