This week's topics include sodium bicarbonate in critically ill people, exercise and cancer survival, Covid vaccination and immune checkpoint inhibitors, and colonoscopy after polyp removal.
Program notes:
0:40 Structured exercise after cancer
1:40 Moderate evidence
2:40 Improves overall survival
3:41 Improves drug penetration
4:00 Colonoscopy intervals after polyp removal
5:00 Five-year cumulative incidence same as three years
6:03 Covid vaccination and immune checkpoint therapy
7:03 Mortality as primary outcome
8:04 Multiple benefits of vaccination
9:03 Other vaccines of benefit?
9:50 Does sodium bicarbonate help in critical illness and shock
10:50 Metabolic acidosis tx
11:50 Largely futile
12:37 End